How Many Calories Are In Pepsi? [Sugar & Nutritional FACTS] Oz can of Pepsi is 150 calories. Compare that to its 16 oz. counterpart, which has 200 calories even. As you might notice, the extra 4 ounces in serving size add on 50 calories. There are four different types of bottle sizes that Pepsi is available in: 20 oz. (250 calories) 1 Liter (436 calories) 1.5 Liter (654 calories) 2 Liter (872 calories)